Lab test

Cortisol Levels Blood Test

This blood test measures cortisol, a hormone made by the adrenal glands.

Typical price

From $109

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

This blood test measures cortisol, a hormone made by the adrenal glands. Cortisol helps the body metabolize carbohydrates, proteins, and fats, regulate blood sugar and blood pressure, and respond to physical and emotional stress. Its level normally follows a daily rhythm, rising in the early morning and falling later in the day. Practitioners order a cortisol test to evaluate suspected adrenal underactivity or overactivity, investigate persistent fatigue, and help interpret a range of hormonal and metabolic symptoms. Because cortisol changes with the time of day, the collection timing is recorded and considered when results are interpreted.

• Cortisol The main adrenal hormone involved in stress response and metabolism.

• Adults with ongoing fatigue or low energy
• People being evaluated for suspected adrenal disorders
• Individuals with unexplained weight change, blood pressure changes, or mood disturbance
• Those being monitored after abnormal adrenal or pituitary findings

• Collection is usually timed for the morning, when cortisol is typically highest; follow your provider's instructions
• Report steroid medications, which can affect cortisol levels
• Follow any fasting or timing instructions provided with your order

Cortisol is assessed against a reference range for the collection time. A low value may point toward reduced adrenal output, while a high value may suggest increased adrenal activity or stress-related causes. Because a single measurement can be influenced by stress, illness, and medications, results are often combined with other testing. A healthcare provider should interpret the level alongside your symptoms and history.

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