Lab test

Casein Allergy Test - Milk Allergy

A casein allergy test measures allergen-specific IgE antibodies produced against casein, the protein that makes up the majority of the protein in cow's milk.

Typical price

From $49

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

A casein allergy test measures allergen-specific IgE antibodies produced against casein, the protein that makes up the majority of the protein in cow's milk. Casein is a major milk allergen and is found in milk and many dairy products. A healthcare provider may order it after a reaction to milk or dairy, or as part of a broader milk protein panel that also includes whey proteins such as beta-lactoglobulin and alpha-lactalbumin. It is a screening tool interpreted with your clinical history.

• Casein-specific IgE Antibodies produced against casein, the main protein in cow's milk; used to assess sensitization to milk.

• People who develop hives, itching, or swelling after consuming milk or dairy
• Individuals with vomiting, diarrhea, or abdominal discomfort linked to dairy
• Those with eczema or skin reactions that flare after milk products
• People who suspect a milk protein reaction rather than lactose intolerance
• Anyone being evaluated as part of a broader cow's milk allergy workup

• No fasting is required before this test
• The sample can be collected at any time of day
• Inform the provider about all medications and supplements you take
• Drinking water beforehand can make the blood draw easier

Results are reported as an IgE level or class for casein. An elevated value may indicate sensitization to casein, but a positive result alone does not prove a clinical allergy. A low or undetectable level makes reactivity to casein less likely, though it does not exclude allergy to whey proteins such as beta-lactoglobulin or alpha-lactalbumin. Because casein is distinct from lactose, this test does not assess lactose intolerance. Discuss results with a healthcare provider before changing your diet.

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