Lab test

Alpha-Lactalbumin Allergy Test - Milk

An alpha-lactalbumin allergy test measures allergen-specific IgE antibodies produced against alpha-lactalbumin, a whey protein found in cow's milk and also present in human breast milk.

Typical price

From $49

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

An alpha-lactalbumin allergy test measures allergen-specific IgE antibodies produced against alpha-lactalbumin, a whey protein found in cow's milk and also present in human breast milk. Alpha-lactalbumin is one of the major milk proteins used to investigate a suspected cow's milk allergy. A healthcare provider may order it after a reaction to milk or dairy, or as part of a wider milk protein panel. It is a screening tool and is interpreted together with symptoms and clinical history.

• Alpha-lactalbumin-specific IgE Antibodies produced against alpha-lactalbumin, a whey protein in cow's milk; used to assess sensitization.

• People who develop hives, itching, or swelling after consuming milk or dairy
• Individuals with vomiting, diarrhea, or abdominal discomfort linked to dairy
• Those with eczema or skin reactions that flare after milk products
• People who suspect a whey protein reaction rather than a casein reaction
• Anyone being evaluated as part of a broader cow's milk allergy workup

• No fasting is required before this test
• The sample can be collected at any time of day
• Inform the provider about all medications and supplements you take
• Drinking water beforehand can make the blood draw easier

Results are reported as an IgE level or class for alpha-lactalbumin. An elevated value may indicate sensitization to this whey protein, but a positive result alone does not prove a clinical allergy. A low or undetectable level makes reactivity to alpha-lactalbumin less likely, though it does not exclude allergy to other milk proteins such as casein. Alpha-lactalbumin appears in the milk of several mammals, so a provider may consider cross-reactivity. Discuss results with a healthcare provider before changing your diet.

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