Lab test

Thyroglobulin Antibody

This blood test measures thyroglobulin antibodies, autoantibodies directed against thyroglobulin, a protein the thyroid uses to store and produce hormone.

Typical price

From $138

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

This blood test measures thyroglobulin antibodies, autoantibodies directed against thyroglobulin, a protein the thyroid uses to store and produce hormone. The presence of these antibodies indicates autoimmune activity against the thyroid and can occur in conditions such as Hashimoto thyroiditis and Graves disease. The test is ordered when a healthcare provider suspects an autoimmune cause for abnormal thyroid function, when thyroid swelling or a goiter is present, and sometimes alongside thyroglobulin measurement in thyroid cancer monitoring. Because antibodies can be present with normal thyroid function, results are interpreted with TSH, Free T4, and clinical findings.

• Thyroglobulin Antibodies Autoantibodies that target thyroglobulin, a thyroid storage protein.

• People with an unexplained abnormal thyroid function test
• Individuals with a family history of autoimmune thyroid disease
• Those with a goiter or thyroid swelling
• People being monitored for thyroid cancer whose thyroglobulin is measured

• Report thyroid medications, biotin, and other supplements to the laboratory
• Follow any timing instructions provided with your order
• Tell your provider if you are pregnant, since thyroid monitoring may change

A positive thyroglobulin antibody result indicates autoimmune thyroid activity, but it does not by itself show whether the thyroid is underactive or overactive. These antibodies can also interfere with thyroglobulin measurements used in thyroid cancer monitoring, which a provider accounts for when interpreting results. The test is read with TSH, Free T4, and symptoms. A healthcare provider should assess the findings and decide whether monitoring or further testing is appropriate.

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