Lab test

Squid Allergy Test - Seafood Allergies

A squid-specific IgE blood test detects antibodies the immune system may produce against proteins in squid, a mollusk often eaten as calamari.

Typical price

From $49

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

A squid-specific IgE blood test detects antibodies the immune system may produce against proteins in squid, a mollusk often eaten as calamari. It is a screening tool for suspected seafood allergy, not a diagnosis by itself. A clinician may order it after a reaction to squid or related seafood, as part of a broader seafood panel, or when symptoms suggest sensitivity to squid.

• Squid-specific IgE Antibodies produced in response to squid proteins, used to assess sensitization.

• Hives, itching, or swelling after eating squid or calamari
• Stomach upset, nausea, or vomiting following squid meals
• Throat tightness or breathing difficulty after seafood exposure
• Testing as part of a broader seafood or shellfish allergy panel
• A history of reactions to other mollusks such as octopus or clams

• No fasting is required for most IgE allergy tests
• Mention antihistamines or other medications to the collector
• Stay hydrated before the blood draw
• One blood sample is typically enough for the squid-specific IgE assay

An elevated squid-specific IgE level may indicate sensitization to squid proteins and can be associated with allergic reactions, but a positive result alone does not prove a clinical allergy. A low or undetectable level lowers the likelihood of allergy without excluding it. Cross-reactivity between mollusks is possible, so a healthcare provider should interpret the result with your history.

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