Lab test

Methadone Screen and Confirmation, Urine

This urine test screens for methadone, a medication used to treat opioid use disorder and severe pain, and confirms any positive result with a more specific method.

Typical price

From $108

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

This urine test screens for methadone, a medication used to treat opioid use disorder and severe pain, and confirms any positive result with a more specific method. Confirmation usually detects both methadone and its primary metabolite, EDDP. Some routine opioid screens do not detect methadone well, so a dedicated test is often needed. Testing supports medication monitoring, adherence checks, and clinical assessment in a confidential laboratory setting.

• Methadone (Screen) An initial immunoassay that detects methadone in urine.
• Methadone (Confirmation) A specific method that verifies methadone when the screen is positive.
• EDDP (Confirmation) The main methadone metabolite, confirmed to distinguish genuine use from possible interference.

• People receiving methadone treatment
• Individuals being monitored for medication adherence
• Patients whose provider needs to confirm methadone use
• People undergoing clinical substance use assessment

• No special preparation is usually needed
• Disclose all prescription and over-the-counter medicines
• Avoid excessive fluid intake just before collection
• Follow instructions from your testing program

A confirmed positive result indicates methadone or its metabolite EDDP is present. Detection time varies with dose, metabolism, and test method, so a positive result does not show exactly when the medication was taken. A negative result may mean methadone is below the detection limit. Discuss your result and its implications for your treatment plan with a healthcare provider.

• Alabama
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• Georgia