Lab test

Lipoprotein Analysis (NMR) Test

NMR lipoprotein analysis is an advanced cholesterol test that measures the number and size of lipoprotein particles in the blood, not just the amount of cholesterol they carry.

Typical price

From $119

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

NMR lipoprotein analysis is an advanced cholesterol test that measures the number and size of lipoprotein particles in the blood, not just the amount of cholesterol they carry. It reports values such as LDL particle number, small LDL particle number, HDL particle number, VLDL particles, and the average size of LDL, HDL, and VLDL particles, along with a standard lipid panel. Clinicians may order it when a person has cardiovascular risk that is not fully explained by standard cholesterol results. It is a detailed risk marker, not a diagnosis, and is interpreted by a healthcare provider.

• Total cholesterol The combined cholesterol carried in the blood.
• LDL cholesterol Low-density lipoprotein cholesterol, a standard cardiovascular risk marker.
• HDL cholesterol High-density lipoprotein cholesterol, often called good cholesterol.
• Triglycerides A type of blood fat that reflects diet and metabolism.
• LDL particle number (LDL-P) The number of LDL particles; a high number can indicate increased cardiovascular risk even when LDL cholesterol looks normal.
• Small LDL particle number The number of small, dense LDL particles, which are considered more atherogenic.
• HDL particle number (HDL-P) The number of HDL particles, a measure of the protective cholesterol transport system.
• Large VLDL particle number The number of large triglyceride-rich VLDL particles.
• LDL particle size The average size of LDL particles; smaller particles are associated with higher risk.
• HDL particle size The average size of HDL particles.
• VLDL particle size The average size of VLDL particles.
• Apolipoprotein B A protein on atherogenic particles that reflects particle number.
• Lipoprotein(a) A genetically influenced cholesterol-carrying particle and cardiovascular risk marker.

• People with cardiovascular risk that standard cholesterol testing does not fully explain
• Individuals with a family history of early heart disease
• Those with diabetes, metabolic syndrome, or high triglycerides
• People who want a detailed assessment of particle number and size
• Anyone whose healthcare provider recommends advanced lipid testing

• Fasting for about 9 to 12 hours is typically required for accurate triglyceride and particle measurements
• Drink water and stay hydrated
• Avoid alcohol and heavy or high-fat meals the night before
• Tell the lab about lipid medications and supplements

The NMR report shows both standard cholesterol values and particle measurements. A high LDL particle number or a high number of small LDL particles may indicate greater cardiovascular risk, even when LDL cholesterol is not elevated. Low HDL particle number may also be relevant, and particle size adds context. Because this is a detailed risk assessment tool, no single number confirms disease. Discuss your NMR results with a healthcare provider, who can interpret the pattern alongside your other risk factors and history.

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