Lab test
Isocyanate MDI Allergy Test
The isocyanate MDI allergy test is a blood test that measures immunoglobulin E (IgE) antibodies against methylene diphenyl diisocyanate (MDI), a reactive chemical used in rigid and flexible foams, adhesives, and coatings.
- Typical price
- From $49
- Results
- 1-3 business days
- Preparation
- See preparation notes below
- Sample
- Blood draw or sample collection at a local center
About this test
The isocyanate MDI allergy test is a blood test that measures immunoglobulin E (IgE) antibodies against methylene diphenyl diisocyanate (MDI), a reactive chemical used in rigid and flexible foams, adhesives, and coatings. It helps determine whether exposure to MDI is contributing to allergy symptoms such as sneezing, nasal congestion, wheezing, coughing, or skin irritation. MDI is a recognized concern in industries that handle polyurethane products, and symptoms often appear or worsen at work. The test is typically ordered for workers with recurring symptoms after handling isocyanate products.
What this test measures
- MDI (methylene diphenyl diisocyanate)-specific IgE Detects IgE antibodies that bind to methylene diphenyl diisocyanate allergens in the blood.
Who this test may be right for
- Workers in foam, insulation, and adhesive manufacturing.
- Construction and trades staff who apply polyurethane products.
- People with asthma or rhinitis that worsens during or after work shifts.
- Those being evaluated for suspected occupational isocyanate allergy.
Before your visit
- No fasting is required.
- Tell the clinician about antihistamines and any other allergy medications.
- Continue prescribed medications unless a healthcare provider advises otherwise.
- Wear short sleeves or a loose top for the blood draw.
Understanding your results
A positive result suggests the body has produced IgE antibodies to MDI, which may indicate a sensitivity contributing to nasal, eye, or airway symptoms after exposure. A negative result makes MDI allergy less likely but does not exclude irritation or reactions to other isocyanates. Because symptoms are often work-related, tracking when they occur can help interpretation. Discuss results with a healthcare provider for a complete assessment.
Order this test online
- Buy online in a few minutes - no doctor's visit needed for most tests.
- Sample collection at a patient service center near you.
- Results are typically ready within 1-3 business days.
- Secure, lab-reviewed results delivered to your account.
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Questions people ask
What does the isocyanate MDI allergy test measure?
It measures MDI-specific IgE antibodies in the blood, which can indicate sensitization to methylene diphenyl diisocyanate.
Where is MDI used?
MDI is used in rigid and flexible foams, adhesives, and coatings, so exposure occurs mainly in industries and trades that handle polyurethane products.
Does this test replace TDI or HDI testing?
No. MDI, TDI, and HDI are distinct isocyanates, so a healthcare provider may order more than one test depending on exposure history.
What is the turnaround time?
Turnaround is typically 1-3 business days.
Do I need to fast before this test?
Follow the lab's instructions.
How long do results take?
Most Isocyanate MDI Allergy Test results are released in 1-3 business days. Specialty testing can take longer.
Is this test right for me?
This page is educational and not medical advice. Talk to a licensed healthcare provider about which tests fit your situation.
LabBookings is an independent directory. We compare test details and pricing information, but we are not a laboratory and we do not perform testing or provide medical advice. Always talk to a licensed healthcare provider about your results and treatment.
Laboratory services are provided by independent, CLIA-certified testing partners. Availability, pricing, and turnaround times can vary by location and are confirmed at checkout.