Lab test

Genital Herpes (HSV-2) Blood Test

This blood test looks for antibodies the immune system produces against herpes simplex virus type 2 (HSV-2).

Typical price

From $45

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

This blood test looks for antibodies the immune system produces against herpes simplex virus type 2 (HSV-2). HSV-2 typically causes genital herpes. The test is type-specific, meaning it helps distinguish HSV-2 from HSV-1. Because it measures antibodies rather than the virus itself, it can take time after exposure for antibodies to become detectable, so timing of the sample matters for interpretation.

• HSV-2-specific IgG antibodies Antibodies produced in response to herpes simplex virus type 2, used to assess prior or current infection.

• You have genital sores or symptoms a clinician wants to evaluate.
• You had possible exposure to genital herpes.
• A partner has genital herpes and you want to know your status.
• You are being screened for sexually transmitted infections that include HSV-2.

• No fasting is required for this blood test.
• The sample can be collected at any time of day.
• Tell the clinician if you have had cold sores or oral herpes, since HSV-1 can affect interpretation.
• Report any antiviral medications you are taking.

A positive HSV-2 antibody result may indicate that the virus is present, while a negative result suggests no evidence of HSV-2 antibodies at the time of testing. Because antibodies can take some weeks to appear after exposure, an early test may be falsely negative. The test does not indicate when the infection was acquired or how often outbreaks occur. Discuss the result and what it means for you with a healthcare provider.

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