Lab test

Hepatitis C RNA Test

A hepatitis C RNA test, also called a nucleic acid amplification test, detects the genetic material of the hepatitis C virus in the blood.

Typical price

From $239

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

A hepatitis C RNA test, also called a nucleic acid amplification test, detects the genetic material of the hepatitis C virus in the blood. It can identify an active infection earlier than antibody testing and is used to confirm exposure flagged by a hepatitis C antibody screen. Clinicians also use it to monitor viral levels in people known to carry the virus.

• Hepatitis C virus RNA The viral genetic material measured by nucleic acid amplification, used to detect and quantify active infection.

• People with a positive hepatitis C antibody result.
• Individuals with possible recent hepatitis C exposure.
• Those with abnormal liver tests or risk factors.
• People being monitored for chronic hepatitis C.
• Anyone with a history of injecting drug use or other blood exposure.

• No fasting is required for hepatitis C RNA testing.
• Take usual medications unless told otherwise.
• Tell the provider about possible exposure and prior hepatitis testing.
• A standard blood draw is used for the sample.
• Timing after exposure may affect detection, so share relevant history.

A detectable hepatitis C RNA result indicates active viral presence, while an undetectable result generally means the virus was not found in that sample. An undetectable RNA with a positive antibody may reflect a resolved past infection. Because detection can depend on timing after exposure, a negative result during the window period may need repeating. Discuss results with a healthcare provider.

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