Lab test

Grapefruit Allergy Test - Citrus Allergies

A grapefruit allergy test uses a blood sample to measure allergen-specific IgE antibodies against grapefruit proteins.

Typical price

From $49

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

A grapefruit allergy test uses a blood sample to measure allergen-specific IgE antibodies against grapefruit proteins. Grapefruit is a citrus fruit, and people who react to one citrus sometimes react to others, so a provider may test several citrus fruits together. The test is a screening tool for suspected food allergy rather than a diagnosis on its own. It may be ordered after a reaction to grapefruit or citrus, or as part of a broader fruit allergy panel. Results are interpreted with symptoms and medical history.

• Grapefruit-specific IgE Antibodies produced against grapefruit proteins; used to assess sensitization to grapefruit.

• People who develop hives, itching, or swelling after eating grapefruit
• Individuals with tingling or itching in the mouth after grapefruit or citrus
• Those with digestive upset, nausea, or diarrhea after citrus fruits
• People with eczema or skin reactions who suspect a citrus trigger
• Anyone who has reacted to other citrus fruits such as orange or lemon

• No fasting is required for this IgE allergy test
• The blood sample can be collected at any time of day
• Tell the provider about all medications you take
• No special diet is needed beforehand

Results are reported as an IgE level or class for grapefruit. An elevated value may indicate sensitization, but sensitization does not always mean a person will react when eating grapefruit. A low or undetectable level makes a true grapefruit allergy less likely, though it does not rule one out. Because citrus fruits share some proteins, a provider may consider cross-reactivity with orange, lemon, or lime. Discuss all results with a healthcare provider before changing your diet.

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