Lab test

Chymopapain (Chymodiactin) Allergy Test

This IgE allergy test uses a blood sample to determine whether you are allergic to chymopapain, a drug that has been used to treat herniated disks through a procedure called chemonucleolysis.

Typical price

From $49

Results

1-3 business days

Preparation

See preparation notes below

Sample

Blood draw or sample collection at a local center

This IgE allergy test uses a blood sample to determine whether you are allergic to chymopapain, a drug that has been used to treat herniated disks through a procedure called chemonucleolysis. Chymopapain is an enzyme derived from papaya. Because exposure to this drug can trigger allergic reactions in sensitive individuals, testing may be requested before a procedure that uses it or when a provider is investigating a possible allergy. The test measures chymopapain-specific IgE antibodies associated with allergic sensitization.

• Chymopapain-specific IgE Measures antibodies associated with an allergic response to chymopapain.

• People being evaluated before a procedure that uses chymopapain
• Individuals who have had symptoms after exposure to chymopapain
• People with a suspected allergy to papaya-derived enzymes
• Those being assessed for a drug-related allergic reaction

• No fasting is required.
• Tell the collector about antihistamines or other allergy medicines you take.
• Follow any instructions given by the collection site.

A positive chymopapain-specific IgE result suggests sensitization to the drug, but it does not predict how severe a reaction would be. A negative result may make allergy less likely, though it does not entirely rule it out. Because chymopapain is used in a medical procedure, results should always be interpreted by a healthcare provider, who can assess the risks and benefits.

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