Lab test

Celiac Disease Antibody Test - IgG & IgA

A celiac disease antibody panel screens for antibodies associated with celiac disease, an immune reaction to gluten.

Typical price
From $249
Results
1-3 business days
Preparation
See preparation notes below
Sample
Blood draw or sample collection at a local center

About this test

A celiac disease antibody panel screens for antibodies associated with celiac disease, an immune reaction to gluten. It typically measures tissue transglutaminase (tTG) IgG and IgA along with gliadin (deamidated gliadin peptide) IgG and IgA. Clinicians order it when symptoms such as diarrhea, bloating, weight loss, or unexplained anemia suggest possible celiac disease, or when screening people at higher risk.

What this test measures

  • Tissue transglutaminase antibody IgA (tTG IgA) The primary screening antibody associated with celiac disease.
  • Tissue transglutaminase antibody IgG (tTG IgG) A marker useful when IgA deficiency is possible.
  • Gliadin antibody IgA (DGP IgA) An antibody against deamidated gliadin that can support celiac screening.
  • Gliadin antibody IgG (DGP IgG) An antibody against deamidated gliadin that can support celiac screening, especially with IgA deficiency.

Who this test may be right for

  • People with chronic diarrhea, bloating, or abdominal discomfort.
  • Individuals with unexplained weight loss or anemia.
  • Those with a family history of celiac disease.
  • People with certain autoimmune or genetic conditions linked to celiac risk.
  • Anyone whose provider suspects gluten-related disease.

Before your visit

  • Continue eating gluten before testing unless told otherwise, since gluten avoidance can affect antibody results.
  • No fasting is required for celiac antibody testing.
  • Take usual medications unless instructed otherwise.
  • Tell the provider about your diet and any prior testing.
  • A standard blood draw is used for the sample.

Understanding your results

Elevated tissue transglutaminase or gliadin antibodies can be associated with celiac disease, but antibody screening is not a diagnosis by itself and is usually followed by confirmatory evaluation. A negative result may be less reliable if a person has been avoiding gluten or has IgA deficiency, which is why IgG markers are included. Discuss the findings with a healthcare provider.

Order this test online

  • Buy online in a few minutes - no doctor's visit needed for most tests.
  • Sample collection at a patient service center near you.
  • Results are typically ready within 1-3 business days.
  • Secure, lab-reviewed results delivered to your account.
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Questions people ask

Which antibodies does this celiac panel measure?

It measures tissue transglutaminase (tTG) IgG and IgA along with gliadin (deamidated gliadin peptide) IgG and IgA.

Why are both IgA and IgG antibodies tested?

IgG markers such as tTG IgG and gliadin IgG help when IgA deficiency could make IgA antibody results unreliable.

Does this test require fasting?

No fasting is required, but continuing to eat gluten before testing is important for accurate antibody results.

Can a negative celiac antibody test rule out celiac disease?

Not always. If gluten has been avoided or IgA deficiency is present, results may be less reliable, so a provider should interpret them.

What does the Celiac Disease Antibody Test - IgG & IgA measure?

Our Celiac Disease Antibody Screening Test screens for the presence of Tissue Transglutaminase antibody (IgG, IgA) and Gliadin antibody (IgG, IgA) in the blood.

Do I need to fast before this test?

Follow the lab's instructions.

How long do results take?

Most Celiac Disease Antibody Test - IgG & IgA results are released in 1-3 business days. Specialty testing can take longer.

Is this test right for me?

This page is educational and not medical advice. Talk to a licensed healthcare provider about which tests fit your situation.

Ready to book? Order online, then visit a patient service center for your sample collection.

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